Evaluating methods for Avian avulavirus-1 whole genome sequencing

Molecular methods for tuberculosis trials: time for whole-genome sequencing?

The fi rst genetic sequencing of Mycobacterium tuberculosis was a momentous achievement that required years of painstaking eff ort and substantial funding. It is remarkable that 15 years later, advances in laboratory techniques and informatics have enabled whole-genome sequencing to be done for hundreds of M tuberculosis isolates, making this information available for epidemiological studies. T...

Whole-Genome Bisulfite Sequencing

Next-generation sequencing technology has enabled genome-wide analysis of 5mC nucleotides at single-nucleotide resolution. Previous methods for whole-genome bisulfite sequencing (WGBS) yielded reduced genomic representation due to required DNA shearing, ligation of methylated sequencing adapters, and bisulfite conversion of unmethylated cytidine residues prior to sequencing. One disadvantage of...

Whole-genome re-sequencing.

DNA sequencing can be used to gain important information on genes, genetic variation and gene function for biological and medical studies. The growing collection of publicly available reference genome sequences will underpin a new era of whole genome re-sequencing, but sequencing costs need to fall and throughput needs to rise by several orders of magnitude. Novel technologies are being develop...

Whole-Genome Bisulfite Sequencing

Next-generation sequencing technology has enabled genome-wide analysis of 5mC nucleotides at single-nucleotide resolution. Previous methods for whole-genome bisulfite sequencing (WGBS) yielded reduced genomic representation due to required DNA shearing, ligation of methylated sequencing adapters, and bisulfite conversion of unmethylated cytidine residues prior to sequencing. One disadvantage of...

Whole Genome Sequencing: An Efficient Approach in Food Safety Management System